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Sichenzia Ross Friedman Ference LLP Advises Fordham Financial on $9.4 million Registered Direct Offering for Ampio Pharmaceuticals.

NEW YORK, December 27, 2011 — New York-based securities law firm, Sichenzia Ross Friedman Ference LLP, announced that it has represented Fordham Financial Management, Inc., as lead placement Agent in a $9.4 million registered direct offering for Ampio Pharmaceuticals, Inc. (NASDAQ: “AMPE”). The offering was placed off an effective S-3 Registration Statement. Summer Street Research Partners and Emerging Growth Equities, Ltd. acted as co- placement agents for the offering. The offering consisted of 2,220,235 shares of common stock at an offering price of $4.25 per share.

“We are pleased for the opportunity to represent Fordham Financial and the other placement agent’s in their support of Ampio,” said Gregory Sichenzia, founding partner of the firm. “This marks the third public offering for a publicly traded pharmaceutical company SRFF has advised on this month.” Earlier, the firm had represented Synergy Pharmaceuticals, Inc. (NASDAQ: “SGYP”) in a $15 million underwritten public offering by Aegis Capital Corp. and Early Bird Capital, Inc., and had represented the underwriter on a $6 million public offering for Novelos Therapeutics, Inc. (“NVLT.OB”).

“Our legal representation in 3 public offerings in one month in the same market sector is significant because it shows promise for additional financings for health care companies in 2012” commented Jeff Fessler, a partner at SRFF.

About Sichenzia Ross Friedman Ference LLP

Sichenzia Ross Friedman Ference LLP is headquartered in New York City and offers a full range of financial and business legal service. SRFF specializes in advising business entities on all securities matters including public offerings, private investment in public entities (PIPEs) deals and international reverse merger transactions. SRFF is also nationally recognized as a leading firm for representation of broker-dealers and securities industry professionals in SEC and FINRA enforcement proceedings as well as securities litigation and arbitration. The Firm is a recognized leader in PIPEs transactions for publicly traded companies and has completed over 400 deals to date, totaling over $2.5 billion since 2001. SRFF maintains dedicated international corporate practice groups and is acknowledged for legal excellence, sectoral expertise and a strong commitment to innovation and client service.

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